คำถามที่พบบ่อย

คำถามจากผู้ใช้และคำตอบ:

อ้างอิง


    การพัฒนาโปรแกรม BONEcheck ได้อธิบายไว้ในเอกสารดังนี้:

    Nguyen D, et al. BONEcheck: a digital tool for personalized bone health assessment.

    MedRxiv: https://www.medrxiv.org/content/10.1101/2023.05.10.23289825v1


    เอกสารที่เป็นพื้นฐานสำหรับ BONEcheck และอธิบายที่มาของเครื่องมือคำนวณความเสี่ยงการเกิดกระดูกหักของสถาบันวิจัย Garvan:

    • 1. Nguyen ND, Pongchaiyakul C, Center JR, Eisman JA, Nguyen TV. Identification of high-risk individuals for hip fracture: a 14-year prospective study. J Bone Miner Res 2005;20(11):1921-8.
    • 2. Nguyen ND, Frost SA, Center JR, Eisman JA, Nguyen TV. Development of a nomogram for individualizing hip fracture risk in men and women. Osteoporos Int 2007 Aug;18(8):1109-17.
    • 3. Nguyen ND, Frost SA, Center JR, Eisman JA, Nguyen TV. Development of Development of Prognostic Nomograms for Individualizing 5-year and 10-year Risks of Fracture. Osteoporos Int 2008;19:1431-44.
    • 4. Nguyen ND, Ahlborg HG, Center JR, Eisman JA, Nguyen TV. Residual lifetime risk of fractures in women and men. J Bone Miner Res 2007 Jun;22(6):781-8.
    • 5. Nguyen TV, Sambrook PN, Kelly PJ, Jones G, Gilbert C, Lord S, Freund J, Eisman JA. Prediction of osteoporotic fractures by postural instability and bone density. Br Med J 1993; 307:1111-1115.
    • 6. Nguyen TV, Eisman JA, Kelly PJ, Sambrook PN. Risk factors for osteoporotic fractures in men. Am J Epidemiol 1996;144:255-263.
    • 7. Nguyen TV, Center JR, Sambrook PN, Eisman JA. Risk factors for proximal humerus, forearm and wrist fractures in elderly men and women: The Dubbo Osteoporosis Epidemiology Study. Am J Epidemiol 2001; 153:587-595.

    เอกสารที่เกี่ยวกับเครื่องมือประเมินความเสี่ยงของการเกิดกระดูกหัก:

  1. 1. Nguyen TV, Eisman JA. Fracture risk assessment: from population to individual. J Clin Densitom 2017;20:368-378.
  2. 2. Nguyen TV. Individualized fracture risk assessment: State-of-the-art and room for improvement. Osteoporosis and Sarcopenia 2018;4:2-10.
  3. 3. Nguyen TV (2020). Toward the era of precision fracture risk assessment. J Clin Endocrinol Metab. pii: dgaa222.
  4. 4. Nguyen TV. Personalized fracture risk assessment: where are we at? Expert Review in Endocrinology and Metabolism 2021;16(4):191-200.
  5. 5. Nguyen TV. Personalised assessment of fracture risk: which tool? Aust J Gen Pract 2022;51:189-190.

    6. เอกสารที่อธิบายเกี่ยวกับแนวคิดอายุของกระดูก:

  6. 1. Ho-Le TP, Tran TS, Bliuc D, Pham HM, Frost SA, Center JR, Eisman JA, Nguyen TV. Epidemiological transition to mortality and refracture following an initial fracture. eLife 2021;10:e61142.
  7. 2. Tran TS, Ho-Le TP, Bliuc D, Abrahemsen B, Hansen L, Vestergaard P, Center JR, Nguyen TV. Skeletal age for mapping the impact of fracture on mortality. eLife 2023.

    8. เอกสารที่อธิบายเกี่ยวกับลักษณะพันธุกรรมของโรคกระดูกพรุน:

  8. 1. Nguyen TV, Eisman JA. Genetic profiling and individualized assessment of fracture risk. Nat Rev Endocrinol 2013;9(3):153-61.
  9. 2. Ho-Le TP, Center JR, Eisman JA, Nguyen HT, Nguyen TV. Prediction of Bone Mineral Density and Fragility Fracture by Genetic Profiling. J Bone Miner Res 2017;32:285-293.
  10. 3. Nguyen TV. Individualized assessment of fracture risk: contribution of "osteogenomic profile". J Clin Densitom 2017;20:353-359.
  11. 4. Ho-Le TP, Pham HM, Center JR, Eisman JA, Nguyen HT, Nguyen TV. Prediction of changes in bone mineral density in the elderly: contribution of "osteogenomic profile". Arch Osteoporos. 2018;13(1):68.
  12. 5. Ho-Le TP, Tran HTT, Center JR, Eisman JA, Nguyen HT, Nguyen TV. Assessing the clinical utility of genetic profiling in fracture risk prediction: a decision curve analysis. Osteoporos Int 2021;32:271–280.

    13. เอกสารที่รายงานการทดสอบความถูกต้องแม่นยำของเครื่องมือ:

  13. 1. Pluskiewicz W, Adamczyk P, Franek E, et al. Ten year probability of osteoporotic fracture in 2012 Polish women assessed by FRAX and nomogram by Nguyen et al – Conformity between methods and their clinical utility. Bone 2010;46(6):1661–67.
  14. 2. Sandhu SK, Nguyen ND, Center JR, Pocock NA, Eisman JA, Nguyen TV. Prognosis of fracture: evaluation of predictive accuracy of the FRAX algorithm and Garvan nomogram. Osteoporos Int 2010;21:863-71.
  15. 3. Leslie WD, Lix LM, Johansson H, Oden A, McCloskey E, Kanis JA, et al. Independent clinical validation of a Canadian FRAX tool: fracture prediction and model calibration. J Bone Miner Res 2010;25(11):2350-8.
  16. 4. Langsetmo L, Nguyen TV, Nguyen ND, et al. Independent external validation of nomograms for predicting risk of low-trauma fracture and hip fracture. CMAJ 2011;183(2):E107–14. doi: 10.1503/cmaj.100458.
  17. 5. Bolland MJ, Siu AT, Mason BH, et al. Evaluation of the FRAX and Garvan fracture risk calculators in older women. J Bone Miner Res 2011;26(2):420–27.
  18. 6. Pluskiewicz W, Adamczyk P, Franek E, et al. FRAX calculator and Garvan nomogram in male osteoporotic population. Aging Male 2014;17(3):174–82.
  19. 7. Holloway-Kew KL, Zhang Y, Betson AG, et al. How well do the FRAX (Australia) and Garvan calculators predict incident fractures? Data from the Geelong Osteoporosis Study. Osteoporos Int 2019;30(10):2129–39.
  20. 8. .Dagan N, Cohen-Stavi C, Leventer-Roberts M, Balicer RD. External validation and comparison of three prediction tools for risk of osteoporotic fractures using data from population based electronic health records: retrospective cohort study. BMJ. 2017 Jan 19;356:i6755. doi: 10.1136/bmj.i6755.
  21. 9. Crandall CJ, Larson J, LaCroix A, Cauley JA, LeBoff MS, Li W, LeBlanc ES, Edwards BJ, Manson JE, Ensrud K. Predicting Fracture Risk in Younger Postmenopausal Women: Comparison of the Garvan and FRAX Risk Calculators in the Women's Health Initiative Study. J Gen Intern Med. 2019 Feb;34(2):235-242.
  22. 10. Inderjeeth CA, Raymond WD. Case finding with GARVAN fracture risk calculator in primary prevention of fragility fractures in older people. Arch Gerontol Geriatr 2020;86:103940. doi: 10.1016/j.archger.2019.103940.

    23. เอกสารที่เกี่ยวข้องอื่นๆ:
  23. 1. Kanis JA, Johnell O, Oden A, Johansson H, McCloskey E. FRAX and the assessment of fracture probability in men and women from the UK. Osteoporos Int 2008;19:385-397.
  24. 2. Borgström F, Johnell O, Kanis JA, Jönsson B, Rehnberg C. At what hip fracture risk is it cost-effective to treat? International intervention thresholds for the treatment of osteoporosis. Osteoporos Int2006 Oct;17(10):1459-71.
  25. 3. Tosteson AN, Melton LJ 3rd, Dawson-Hughes B, Baim S, Favus MJ, Khosla S, Lindsay RL. Cost-effective osteoporosis treatment thresholds: the United States perspective. 20. Osteoporos Int 2008 Feb 22.